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Target
Protein Wnt-3a
Ligand
BDBM89425
Substrate
n/a
IC50
803±n/a nM
Citation
 PubChem, PC Dose response validation of uHTS Gli-SUFU antagonist hits in a Wnt3a luminescent reporter assay PubChem Bioassay (2012)[AID] 
Target
Name:
Protein Wnt-3a
Synonyms:
WNT3A_MOUSE | Wnt-3a | Wnt3a | protein Wnt-3a precursor
Type:
PROTEIN
Mol. Mass.:
39269.29
Organism:
Mus musculus
Description:
ChEMBL_813156
Residue:
352
Sequence:
MAPLGYLLVLCSLKQALGSYPIWWSLAVGPQYSSLSTQPILCASIPGLVPKQLRFCRNYVEIMPSVAEGVKAGIQECQHQFRGRRWNCTTVSNSLAIFGPVLDKATRESAFVHAIASAGVAFAVTRSCAEGSAAICGCSSRLQGSPGEGWKWGGCSEDIEFGGMVSREFADARENRPDARSAMNRHNNEAGRQAIASHMHLKCKCHGLSGSCEVKTCWWSQPDFRTIGDFLKDKYDSASEMVVEKHRESRGWVETLRPRYTYFKVPTERDLVYYEASPNFCEPNPETGSFGTRDRTCNVSSHGIDGCDLLCCGRGHNARTERRREKCHCVFHWCCYVSCQECTRVYDVHTCK
  
Inhibitor
Name:
BDBM89425
Synonyms:
3-(benzenesulfonyl)-N-(3-ethyl-4-methoxy-1,3-benzothiazol-2-ylidene)propanamide | 3-besyl-N-(3-ethyl-4-methoxy-1,3-benzothiazol-2-ylidene)propionamide | MLS001237985 | N-(3-ethyl-4-methoxy-1,3-benzothiazol-2-ylidene)-3-(phenylsulfonyl)propanamide | SMR000806292 | cid_7153852
Type:
Small organic molecule
Emp. Form.:
C19H20N2O4S2
Mol. Mass.:
404.503
SMILES:
CCn1c2c(OC)cccc2sc1=NC(=O)CCS(=O)(=O)c1ccccc1 |w:13.15|
Structure:
Search PDB for entries with ligand similarity: