Reaction Details Report a problem with these data
Target
Nuclear receptor subfamily 5 group A member 2
Ligand
BDBM95516
Substrate
n/a
IC50
>1330±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) PubChem Bioassay (2013)[AID] 
Target
Name:
Nuclear receptor subfamily 5 group A member 2
Synonyms:
Alpha-1-fetoprotein transcription factor | B1-binding factor | B1F | CPF | CYP7A promoter-binding factor | FTF | Hepatocytic transcription factor | LRH-1 | Liver Receptor Homolog 1 | NR5A2 | NR5A2_HUMAN | Nuclear receptor subfamily 5 group A member 2 | hB1F | nuclear receptor subfamily 5 group A member 2 isoform 2
Type:
Nuclear Hormone Receptor
Mol. Mass.:
61341.37
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
541
Sequence:
MSSNSDTGDLQESLKHGLTPIGAGLPDRHGSPIPARGRLVMLPKVETEALGLARSHGEQGQMPENMQVSQFKMVNYSYDEDLEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRMRGGRNKFGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPSDLTISSAIQNIHSASKGLPLNHAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPESIMGYSYMDSYQTSSPASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLSTFGLMCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKEGSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLNGDVPYNNLLIEMLHAKRA
  
Inhibitor
Name:
BDBM95516
Synonyms:
MLS000687173 | N-[5-(2,5-dichlorobenzyl)thiazol-2-yl]acetamide | N-[5-[(2,5-dichlorophenyl)methyl]-1,3-thiazol-2-yl]acetamide | N-[5-[(2,5-dichlorophenyl)methyl]-2-thiazolyl]acetamide | N-[5-[[2,5-bis(chloranyl)phenyl]methyl]-1,3-thiazol-2-yl]ethanamide | SMR000284123 | cid_685884
Type:
Small organic molecule
Emp. Form.:
C12H10Cl2N2OS
Mol. Mass.:
301.192
SMILES:
CC(=O)Nc1ncc(Cc2cc(Cl)ccc2Cl)s1
Structure:
Search PDB for entries with ligand similarity: