Reaction Details
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Report a problem with these dataTarget
Nuclear receptor subfamily 5 group A member 2
Ligand
BDBM95530
Substrate
n/a
IC50
4160±n/a nM
Citation
PubChem, PC Luminescence-based cell-based high throughput dose response assay for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) PubChem Bioassay (2013)[AID] More Info.:
Target
Name:
Nuclear receptor subfamily 5 group A member 2
Synonyms:
Alpha-1-fetoprotein transcription factor | B1-binding factor | B1F | CPF | CYP7A promoter-binding factor | FTF | Hepatocytic transcription factor | LRH-1 | Liver Receptor Homolog 1 | NR5A2 | NR5A2_HUMAN | Nuclear receptor subfamily 5 group A member 2 | hB1F | nuclear receptor subfamily 5 group A member 2 isoform 2
Type:
Nuclear Hormone Receptor
Mol. Mass.:
61341.37
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
541
Sequence:
MSSNSDTGDLQESLKHGLTPIGAGLPDRHGSPIPARGRLVMLPKVETEALGLARSHGEQGQMPENMQVSQFKMVNYSYDEDLEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRMRGGRNKFGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPSDLTISSAIQNIHSASKGLPLNHAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPESIMGYSYMDSYQTSSPASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLSTFGLMCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKEGSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLNGDVPYNNLLIEMLHAKRA
Inhibitor
Name:
BDBM95530
Synonyms:
5-nitro-N-(2-oxidanyl-5-sulfamoyl-phenyl)furan-2-carboxamide | MLS000775905 | N-(2-hydroxy-5-sulfamoyl-phenyl)-5-nitro-2-furamide | N-(2-hydroxy-5-sulfamoylphenyl)-5-nitro-2-furancarboxamide | N-(2-hydroxy-5-sulfamoylphenyl)-5-nitrofuran-2-carboxamide | SMR000371034 | cid_3648622
Type:
Small organic molecule
Emp. Form.:
C11H9N3O7S
Mol. Mass.:
327.27
SMILES:
NS(=O)(=O)c1ccc(O)c(NC(=O)c2ccc(o2)[N+]([O-])=O)c1
Structure:
