Reaction Details Report a problem with these data
Target
Nuclear receptor subfamily 5 group A member 2
Ligand
BDBM95566
Substrate
n/a
IC50
594.34±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) PubChem Bioassay (2013)[AID] 
Target
Name:
Nuclear receptor subfamily 5 group A member 2
Synonyms:
Alpha-1-fetoprotein transcription factor | B1-binding factor | B1F | CPF | CYP7A promoter-binding factor | FTF | Hepatocytic transcription factor | LRH-1 | Liver Receptor Homolog 1 | NR5A2 | NR5A2_HUMAN | Nuclear receptor subfamily 5 group A member 2 | hB1F | nuclear receptor subfamily 5 group A member 2 isoform 2
Type:
Nuclear Hormone Receptor
Mol. Mass.:
61341.37
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
541
Sequence:
MSSNSDTGDLQESLKHGLTPIGAGLPDRHGSPIPARGRLVMLPKVETEALGLARSHGEQGQMPENMQVSQFKMVNYSYDEDLEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRMRGGRNKFGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPSDLTISSAIQNIHSASKGLPLNHAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPESIMGYSYMDSYQTSSPASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLSTFGLMCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKEGSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLNGDVPYNNLLIEMLHAKRA
  
Inhibitor
Name:
BDBM95566
Synonyms:
2-[(5-keto-2H-1,2,4-triazin-3-yl)thio]-N-p-phenetyl-acetamide | MLS001218308 | N-(4-Ethoxy-phenyl)-2-(5-oxo-4,5-dihydro-[1,2,4]triazin-3-ylsulfanyl)-acetamide | N-(4-ethoxyphenyl)-2-[(5-oxidanylidene-2H-1,2,4-triazin-3-yl)sulfanyl]ethanamide | N-(4-ethoxyphenyl)-2-[(5-oxo-2H-1,2,4-triazin-3-yl)sulfanyl]acetamide | N-(4-ethoxyphenyl)-2-[(5-oxo-2H-1,2,4-triazin-3-yl)thio]acetamide | SMR000613470 | cid_6484709
Type:
Small organic molecule
Emp. Form.:
C13H14N4O3S
Mol. Mass.:
306.34
SMILES:
CCOc1ccc(NC(=O)CSc2nncc(=O)[nH]2)cc1
Structure:
Search PDB for entries with ligand similarity: