Reaction Details Report a problem with these data
Target
Low molecular weight phosphotyrosine protein phosphatase
Ligand
BDBM34164
Substrate
n/a
IC50
>80000±n/a nM
Citation
 PubChem, PC Dose response confirmation of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, in an orthogonal absorbance-based assay PubChem Bioassay (2013)[AID] 
Target
Name:
Low molecular weight phosphotyrosine protein phosphatase
Synonyms:
3.1.3.2 | 3.1.3.48 | ACP1 | Adipocyte acid phosphatase | LMW-PTP | LMW-PTPase | LMWPTP | Low molecular weight cytosolic acid phosphatase | PPAC_HUMAN | Red cell acid phosphatase 1 | low molecular weight phosphotyrosine protein phosphatase isoform c
Type:
n/a
Mol. Mass.:
18042.81
Organism:
Homo sapiens (Human)
Description:
P24666
Residue:
158
Sequence:
MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRGQSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSYDPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
  
Inhibitor
Name:
BDBM34164
Synonyms:
(3E)-3-[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-ylidene]-6-methoxy-2-quinolinone | (3E)-3-[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-ylidene]-6-methoxy-carbostyril | (3E)-3-[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-ylidene]-6-methoxy-quinolin-2-one | (3E)-3-[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-ylidene]-6-methoxyquinolin-2-one | 3-[5-(4-Fluoro-phenyl)-[1,2,4]oxadiazol-3-yl]-6-methoxy-quinolin-2-ol | MLS000071054 | SMR000015028 | cid_5423532
Type:
Small organic molecule
Emp. Form.:
C18H12FN3O3
Mol. Mass.:
337.3046
SMILES:
COc1ccc2[nH]c(=O)c(cc2c1)-c1noc(n1)-c1ccc(F)cc1
Structure:
Search PDB for entries with ligand similarity: