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Target
Trace amine-associated receptor 1
Ligand
BDBM96614
Substrate
n/a
EC50
125.09±n/a nM
Citation
 PubChem, PC Fluorescence-based cell-based high throughput dose response assay to identify agonists of the human trace amine associated receptor 1 (TAAR1) PubChem Bioassay (2013)[AID] 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TA1 | TAAR1 | TAAR1_HUMAN | TAR1 | TRAR1 | trace amine-associated receptor 1
Type:
PROTEIN
Mol. Mass.:
39107.47
Organism:
Homo sapiens (Human)
Description:
ChEMBL_792734
Residue:
339
Sequence:
MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNWLIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRGGCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQIGLEMKNGISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFNPMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS
  
Inhibitor
Name:
BDBM96614
Synonyms:
2-(3,4-Dihydro-1H-isoquinolin-2-yl)-3,3,3-trifluoro-2-propionylamino-propionic acid ethyl ester | 2-(3,4-dihydro-1H-isoquinolin-2-yl)-3,3,3-trifluoro-2-(1-oxopropylamino)propanoic acid ethyl ester | 2-(3,4-dihydro-1H-isoquinolin-2-yl)-3,3,3-trifluoro-2-propionamido-propionic acid ethyl ester | MLS000554893 | SMR000147010 | cid_3590464 | ethyl 2-(3,4-dihydro-1H-isoquinolin-2-yl)-3,3,3-trifluoro-2-(propanoylamino)propanoate | ethyl 2-(3,4-dihydro-1H-isoquinolin-2-yl)-3,3,3-tris(fluoranyl)-2-(propanoylamino)propanoate
Type:
Small organic molecule
Emp. Form.:
C17H21F3N2O3
Mol. Mass.:
358.3554
SMILES:
CCOC(=O)C(NC(=O)CC)(N1CCc2ccccc2C1)C(F)(F)F
Structure:
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