Reaction Details Report a problem with these data
Target
P2X purinoceptor 3
Ligand
BDBM106027
Substrate
n/a
Meas. Tech.
Inhibiton Assay
IC50
83±n/a nM
Citation
 Kai, H; Taoda, Y; Endoh, T; Asahi, K; Tobinaga, H Pyrolinone derivative and pharmaceutical composition comprising the same US Patent  US8575197 Publication Date 11/5/2013 
Target
Name:
P2X purinoceptor 3
Synonyms:
ATP receptor | Glucocorticoid receptor | P2RX3 | P2RX3_HUMAN | P2X purinoceptor 3 | P2X purinoceptor 3 (P2RX3) | P2X purinoceptor 3 (P2X3) | P2X3 | P2X3 purinoceptor | Purinergic receptor | p2x3 + hsa
Type:
Protein
Mol. Mass.:
44292.02
Organism:
Homo sapiens (Human)
Description:
P56373
Residue:
397
Sequence:
MNCISDFFTYETTKSVVVKSWTIGIINRVVQLLIISYFVGWVFLHEKAYQVRDTAIESSVVTKVKGSGLYANRVMDVSDYVTPPQGTSVFVIITKMIVTENQMQGFCPESEEKYRCVSDSQCGPERLPGGGILTGRCVNYSSVLRTCEIQGWCPTEVDTVETPIMMEAENFTIFIKNSIRFPLFNFEKGNLLPNLTARDMKTCRFHPDKDPFCPILRVGDVVKFAGQDFAKLARTGGVLGIKIGWVCDLDKAWDQCIPKYSFTRLDSVSEKSSVSPGYNFRFAKYYKMENGSEYRTLLKAFGIRFDVLVYGNAGKFNIIPTIISSVAAFTSVGVGTVLCDIILLNFLKGADQYKAKKFEEVNETTLKIAALTNPVYPSDQTTAEKQSTDSGAFSIGH
  
Inhibitor
Name:
BDBM106027
Synonyms:
US8575197, I-537
Type:
Small organic molecule
Emp. Form.:
C30H32N2O5
Mol. Mass.:
500.5855
SMILES:
CC(C)C(=O)C1C(N(C(=O)C1=O)c1ccc(cc1)-c1ccc(C)o1)c1ccccc1CCC(=O)N(C)C
Structure:
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