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Target
5-hydroxytryptamine receptor 2A
Ligand
BDBM114616
Substrate
n/a
Meas. Tech.
Late stage for the probe development effort to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A)
EC50
76083±n/a nM
Citation
 PubChem, PC Late stage for the probe development effort to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A): Luminescence-based cell-based high throughput dose response assay for agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A) PubChem Bioassay (2013)[AID] 
Target
Name:
5-hydroxytryptamine receptor 2A
Synonyms:
5-HT-2 | 5-HT-2A | 5-hydroxytryptamine receptor 2A | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_MOUSE | Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor | Htr2 | Htr2a | Serotonin 2a (5-HT2a) receptor
Type:
Enzyme
Mol. Mass.:
52843.00
Organism:
Mus musculus (Mouse)
Description:
P35363
Residue:
471
Sequence:
MEILCEDNISLSSIPNSLMQLGDDSRLYPNDFNSRDANTSEASNWTIDAENRTNLSCEGYLPPTCLSILHLQEKNWSALLTTVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVAFFIPLTIMVITYFLTIKSLQKEATLCVSDLSTRAKLSSFSFLPQSSLSSEKLFQRSIHREPGSYAGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNENVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENRKPLQLILVNTIPTLAYKSSQLQVGQKKNSQEDAEPTANDCSMVTLGNQHSEEMCTDNIETVNEKVSCV
  
Inhibitor
Name:
BDBM114616
Synonyms:
2-[4-[(5-methyl-2-furanyl)methyl]-1-piperazinyl]pyrimidine | 2-[4-[(5-methyl-2-furyl)methyl]piperazino]pyrimidine | 2-[4-[(5-methylfuran-2-yl)methyl]piperazin-1-yl]pyrimidine | SR-01000672677 | SR-01000672677-2 | cid_783224
Type:
Small organic molecule
Emp. Form.:
C14H18N4O
Mol. Mass.:
258.3189
SMILES:
Cc1ccc(CN2CCN(CC2)c2ncccn2)o1
Structure:
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