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TargetAlpha trans-inducing protein (VP16)
LigandBDBM36943
Substrate/Competitorn/a
Meas. Tech.Counterscreen for inhibitors of COUP-TFII (NR2F2): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16)
IC50 85392±n/a nM
Citation PubChem, PC Counterscreen for inhibitors of COUP-TFII (NR2F2): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16) PubChem Bioassay(2013)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Alpha trans-inducing protein (VP16)
Name:Alpha trans-inducing protein (VP16)
Synonyms:transactivating tegument protein VP16
Type:PROTEIN
Mol. Mass.:54325.13
Organism:Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus1)
Description:EBI_100271
Residue:490
Sequence:
MDLLVDELFADMNADGASPPPPRPAGGPKNTPAAPPLYATGRLSQAQLMPSPPMPVPPAA
LFNRLLDDLGFSAGPALCTMLDTWNEDLFSALPTNADLYRECKFLSTLPSDVVEWGDAYV
PERTQIDIRAHGDVAFPTLPATRDGLGLYYEALSRFFHAELRAREESYRTVLANFCSALY
RYLRASVRQLHRQAHMRGRDRDLGEMLRATIADRYYRETARLARVLFLHLYLFLTREILW
AAYAEQMMRPDLFDCLCCDLESWRQLAGLFQPFMFVNGALTVRGVPIEARRLRELNHIRE
HLNLPLVRSAATEEPGAPLTTPPTLHGNQARASGYFMVLIRAKLDSYSSFTTSPSEAVMR
EHAYSRARTKNNYGSTIEGLLDLPDDDAPEEAGLAAPRLSFLPAGHTRRLSTAPPTDVSL
GDELHLDGEDVAMAHADALDDFDLDMLGDGDSPGPGFTPHDSAPYGALDMADFEFEQMFT
DALGIDEYGG
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM36943
NameBDBM36943
Synonyms:(8-fluoro-5H-pyrimid[5,4-b]indol-4-yl)-(3-isopropoxypropyl)amine | 8-fluoranyl-N-(3-propan-2-yloxypropyl)-5H-pyrimido[5,4-b]indol-4-amine | 8-fluoro-N-(3-propan-2-yloxypropyl)-5H-pyrimido[5,4-b]indol-4-amine | MLS000040860 | SMR000045926 | cid_664895
TypeSmall organic molecule
Emp. Form.C16H19FN4O
Mol. Mass.302.3467
SMILESCC(C)OCCCNc1ncnc2c3cc(F)ccc3[nH]c12
Structure
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n/a