Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 1
Ligand
BDBM119192
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
Ki
0.8±n/a nM
Citation
 Nettekoven, M; Norcross, R; Polara, A Dihydrooxazol-2-amine derivatives US Patent  US8673950 Publication Date 3/18/2014 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TAAR1_RAT | Ta1 | Taar1 | Tar1 | Trace amine receptor 1 (TARR1) | Trace amine-associated receptor 1 | Trace amine-associated receptor 1 (TAAR1) | Trace amine-associated receptor1 | Trar1
Type:
Enzyme
Mol. Mass.:
38034.73
Organism:
Rattus norvegicus (Rat)
Description:
Q923Y9
Residue:
332
Sequence:
MHLCHNSANISHTNSNWSRDVRASLYSLISLIILTTLVGNLIVIISISHFKQLHTPTNWLLHSMAVVDFLLGCLVMPYSMVRTVEHCWYFGELFCKLHTSTDIMLSSASILHLAFISIDRYYAVCDPLRYKAKINLAAIFVMILISWSLPAVFAFGMIFLELNLEGVEELYHNQVFCLRGCFPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRANLQVGLEGESRAPQSKETKAAKTLGIMVGVFLLCWCPFFFCMVLDPFLGYVIPPTLNDTLNWFGYLNSAFNPMVYAFFYPWFRRALKMVLFGKIFQKDSSRSKLFL
  
Inhibitor
Name:
BDBM119192
Synonyms:
US8673950, 59
Type:
Small organic molecule
Emp. Form.:
C16H16N6O
Mol. Mass.:
308.3378
SMILES:
NC1=N[C@@H](CCc2ccc(Nc3ncc(cn3)C#N)cc2)CO1 |r,t:1|
Structure:
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