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TargetProkineticin receptor 2 (PRK2)
LigandBDBM121107
Substrate/Competitorn/a
Meas. Tech.Calcium Mobilization Assay
Temperature310.15±n/a K
Ki 2.87±n/a nM
Commentsextracted
Citation Zhou, QLi, JHuang, Q Prokineticin receptor antagonists and uses thereof US Patent US8722896 Publication Date 5/13/2014
More Info.:Get all data from this article,  Assay Method
 
Prokineticin receptor 2 (PRK2)
Name:Prokineticin receptor 2 (PRK2)
Synonyms:n/a
Type:Enzyme
Mol. Mass.:44473.96
Organism:Cricetulus griseus (Chinese hamster)
Description:G3H407
Residue:391
Sequence:
MPPAGINMASQNKNTSFAPDLNPSQDHISSLPFNFSYSDYDLPLDGDEDMTKTQTFFAAK
IVIGVALAGIMLVCGIGNFVFIAALARYKKLRNLTNLLIANLAISDFLVAIVCCPFEMDY
YVVRQLSWEHGHVLCASVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLKPRMNYQTASFL
IALVWMVSILIAIPSAYFTTETILDIVKNQEKIFCGQIWPVDQQLYYKSYFLFVFGLEFV
GPVVAMTLCYARISQELWFKAVPGFQTEQIRKRLRCRRKTVLLLMGILTAYVLCWAPFYG
FTIVRDFFPTVFVKEKHYLTAFYVVECIAMSNSMINTICFVTVKNNTMKYFKKMLLLHWQ
PSRYGSKSSADLDLKTSGVPATEEVDCIRLK
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM121107
NameBDBM121107
Synonyms:US8722896, (-)-(3R)-1-(Indolin-7-ylmethyl)- N-(9-chloro-3,4-dihydro-2H-1,5- benzodioxepin-7-ylmethyl)-N- isobutylpyrrolidine-3- carboxamide
TypeSmall organic molecule
Emp. Form.C28H36ClN3O3
Mol. Mass.498.057
SMILESCC(C)CN(Cc1cc(Cl)c2OCCCOc2c1)C(=O)[C@@H]1CCN(Cc2cccc3CCNc23)C1 |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a