Target
Phospholipase A2 group V
Ligand
BDBM153281
Substrate
n/a
Meas. Tech.
sPLA2V Activity Assay
pH
7.5±n/a
Temperature
298.15±n/a K
IC50
2.783e+4± 1.42e+3 nM
Comments
extracted
Citation
 Bukhari, SNZhang, XJantan, IZhu, HLAmjad, MWMasand, VH Synthesis, Molecular Modeling, and Biological Evaluation of Novel 1, 3-Diphenyl-2-propen-1-one Based Pyrazolines as Anti-inflammatory Agents. Chem Biol Drug Des 85:729-42 (2015) [PubMed]  Article 
Target
Name:
Phospholipase A2 group V
Synonyms:
PA2G5_HUMAN | PLA2G5 | Phospholipase A2 group V | Secretory phospholipase A2, group V (sPLA2-V)
Type:
Protein
Mol. Mass.:
15682.61
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
138
Sequence:
MKGLLPLAWFLACSVPAVQGGLLDLKSMIEKVTGKNALTNYGFYGCYCGWGGRGTPKDGTDWCCWAHDHCYGRLEEKGCNIRTQSYKYRFAWGVVTCEPGPFCHVNLCACDRKLVYCLKRNLRSYNPQYQYFPNILCS
  
Inhibitor
Name:
BDBM153281
Synonyms:
1-Benzofuran-2-yl-3-(4,7-dimethoxy-naphthalen-1-yl)-propenone (2)
Type:
Small organic molecule
Emp. Form.:
C23H18O4
Mol. Mass.:
358.3866
SMILES:
COc1ccc2c(OC)ccc(\C=C\C(=O)c3cc4ccccc4o3)c2c1
Structure:
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