Reaction Details Report a problem with these data
Target
Mu-type opioid receptor
Ligand
BDBM179887
Substrate
n/a
Meas. Tech.
n/a
pH
7.5±n/a
Temperature
298.15±n/a K
Ki
0.11±n/a nM
IC50
26±n/a nM
Comments
extracted
Citation
 Blumberg, LC; Deaver, D; Eyerman, D Morphan and morphinan analogues, and methods of use US Patent  US9133125 Publication Date 9/15/2015 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM179887
Synonyms:
US10287250, Compound C.5 | US10752592, Compound TABLE C.-9 | US9133125, Table C, Compound 5 | US9656961, Example 00152
Type:
Small organic molecule
Emp. Form.:
C17H25NO2
Mol. Mass.:
275.3859
SMILES:
COCCN1CC[C@]2(C)[C@@H](C)[C@H]1Cc1ccc(O)cc21 |r,TLB:3:4:9:19.13.12|
Structure:
Search PDB for entries with ligand similarity: