Reaction Details
Report a problem with these data
Report a problem with these dataTarget
Amine oxidase
Ligand
BDBM185657
Substrate
n/a
Meas. Tech.
Inhibition Assay
pH
7.2±n/a
Temperature
303.15±n/a K
IC50
3000000±n/a nM
Comments
extracted
More Info.:
Target
Name:
Amine oxidase
Synonyms:
Lysyl oxdiase (PPLO)
Type:
Enzyme
Mol. Mass.:
89638.03
Organism:
Komagataella pastoris (Yeast) (Pichia pastoris)
Description:
Q96X16
Residue:
787
Sequence:
MRLTNLLSLTTLVALAVAVPDFYQKREAVSSKEAALLRRDASAECVSNENVEIEAPKTNIWTSLAKEEVQEVLDLLHSTYNITEVTKADFFSNYVLWIETLKPNKTEALTYLDEDGDLPPRNARTVVYFGEGEEGYFEELKVGPLPVSDETTIEPLSFYNTNGKSKLPFEVGHLDRIKSAAKSSFLNKNLNTTIMRDVLEGLIGVPYEDMGCHSAAPQLHDPATGATVDYGTCNINTENDAENLVPTGFFFKFDMTGRDVSQWKMLEYIYNNKVYTSAEELYEAMQKDDFVTLPKIDVDNLDWTVIQRNDSAPIRHLDDRKSPRLVEPEGRRWAYDGEEEYFSWMDWGFYTSWSRDTGISFYDITFKGERIVYELSLQELIAEYGSDDPFNQHTFYSDISYGVGNRFSLVPGYDCPATAGYFTTDTFEYDEFYNRTLSYCVFENQEDYSLLRHTGASYSAITQNPTLNVRFISTIGNYDYNFLYKFFLDGTLEVSVRAAGYIQAGYWNPETSAPYGLKIHDVLSGSFHDHVLNYKVDLDVGGTKNRASKYVMKDVDVEYPWAPGTVYNTKQIAREVLEKEDFNGINWPENGQGILLIESAEETNSFGNPRAYNIMPGGGGVHRIVKNSRSGPETQNWARSNLFLTKHKDEELRSSTALNTNALYDPPVNFNAFLDDESLDGEDIVAWVNLGLHHLPNSNDLPNTIFSTAHASFMLTPFNYFDSENSRDTTQQVFYTYDDETEESNWEFYGNDWSSCGLEVPEPNFEDYTYGRGTRINKKMTNSDEVY
Inhibitor
Name:
BDBM185657
Synonyms:
US9161922, Table 3, Compound 2
Type:
Small organic molecule
Emp. Form.:
C12H20N4O4
Mol. Mass.:
284.3116
SMILES:
CCOC(=O)CNC(=O)CNC(=O)C(N)CC#CCN
Structure:
