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Target5-hydroxytryptamine receptor 2B (5HT2B)
LigandBDBM186932
Substrate/Competitorn/a
Meas. Tech.Radioligand Binding Assay
pH7.4±n/a
Ki 2358±n/a nM
Commentsextracted
Citation Besnard, JHopkins, ALGilbert, IRuda, GFAbecassis, K Morpholino compounds, uses and methods US Patent US9079895 Publication Date 7/14/2015
More Info.:Get all data from this article,  Assay Method
 
5-hydroxytryptamine receptor 2B (5HT2B)
Name:Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor
Synonyms:5-HT2 | 5-HT2B | 5-hydroxytryptamine receptor 2B | HTR2B
Type:Enzyme
Mol. Mass.:53610.91
Organism:Mus musculus (Mouse)
Description:Q02152
Residue:479
Sequence:
MASSYKMSEQSTTSEHILQKTCDHLILTNRSGLETDSVAEEMKQTVEGQGHTVHWAALLI
LAVIIPTIGGNILVILAVALEKRLQYATNYFLMSLAIADLLVGLFVMPIALLTIMFEAIW
PLPLALCPAWLFLDVLFSTASIMHLCAISLDRYIAIKKPIQANQCNSRATAFIKITVVWL
ISIGIAIPVPIKGIETDVINPHNVTCELTKDRFGSFMVFGSLAAFFAPLTIMVVTYFLTI
HTLQKKAYLVKNKPPQRLTRWTVPTVFLREDSSFSSPEKVAMLDGSHRDKILPNSSDETL
MRRMSSVGKRSAQTISNEQRASKALGVVFFLFLLMWCPFFITNLTLALCDSCNQTTLKTL
LEIFVWIGYVSSGVNPLIYTLFNKTFREAFGRYITCNYRATKSVKALRKFSSTLCFGNSM
VENSKFFTKHGIRNGINPAMYQSPMRLRSSTIQSSSIILLDTLLTENDGDKAEEQVSYI
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  Blast E-value cutoff:
BDBM186932
NameBDBM186932
Synonyms:US9079895, 22r
TypeSmall organic molecule
Emp. Form.C21H23ClN2O3
Mol. Mass.386.872
SMILESClc1cccc(OC[C@H]2CN(CC(=O)N3CCc4ccccc34)CCO2)c1 |r|
Structure
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