Reaction Details Report a problem with these data
Target
Large envelope protein
Ligand
BDBM289780
Substrate
n/a
Meas. Tech.
HBSAg ELISA assay
EC50
90.0±n/a nM
Citation
 Fu, J; Jin, X; Lee, P; Lu, P; Young, JM Tetracyclic pyridone compounds as antivirals US Patent  US10093673 Publication Date 10/9/2018 
Target
Name:
Large envelope protein
Synonyms:
HBSAG_HBVD3 | S
Type:
n/a
Mol. Mass.:
42772.52
Organism:
Hepatitis B virus
Description:
P03138
Residue:
389
Sequence:
MGQNLSTSNPLGFFPDHQLDPAFRANTANPDWDFNPNKDTWPDANKVGAGAFGLGFTPPHGGLLGWSPQAQGILQTLPANPPPASTNRQSGRQPTPLSPPLRNTHPQAMQWNSTTFHQTLQDPRVRGLYFPAGGSSSGTVNPVLTTASPLSSIFSRIGDPALNMENITSGFLGPLLVLQAGFFLLTRILTIPQSLDSWWTSLNFLGGTTVCLGQNSQSPTSNHSPTSCPPTCPGYRWMCLRRFIIFLFILLLCLIFLLVLLDYQGMLPVCPLIPGSSTTSTGPCRTCMTTAQGTSMYPSCCCTKPSDGNCTCIPIPSSWAFGKFLWEWASARFSWLSLLVPFVQWFVGLSPTVWLSVIWMMWYWGPSLYSILSPFLPLLPIFFCLWVYI
  
Inhibitor
Name:
BDBM289780
Synonyms:
US10093673, Compound 7.2
Type:
Small organic molecule
Emp. Form.:
C23H26FNO7
Mol. Mass.:
447.4534
SMILES:
COCCCOc1cc2[C@@H]3OCC(C)(C)C3n3cc(C(O)=O)c(=O)c(F)c3-c2cc1OC |r|
Structure:
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