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Target
Alpha-synuclein
Ligand
BDBM207942
Substrate
n/a
Meas. Tech.
In Vitro Inhibition Assay
EC50
27±n/a nM
Citation
 Griffioen, G; Van Dooren, T; Rojas De La Parra, V; Allasia, S; Marchand, A; Kilonda, A; Chaltin, P Compounds for the treatment of neurodegenerative diseases US Patent  US9266832 Publication Date 2/23/2016 
Target
Name:
Alpha-synuclein
Synonyms:
NACP | PARK1 | SNCA | SYUA_HUMAN
Type:
Protein
Mol. Mass.:
14451.42
Organism:
Homo sapiens (Human)
Description:
P37840
Residue:
140
Sequence:
MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTKEQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDPDNEAYEMPSEEGYQDYEPEA
  
Inhibitor
Name:
BDBM207942
Synonyms:
US9266832, Cpd099
Type:
Small organic molecule
Emp. Form.:
C24H19ClF2N2O
Mol. Mass.:
424.87
SMILES:
Fc1cccc(Cc2ccc(C(=O)NCCc3c[nH]c4ccc(Cl)cc34)c(F)c2)c1
Structure:
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