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Target
Alpha-synuclein
Ligand
BDBM207958
Substrate
n/a
Meas. Tech.
In Vitro Inhibition Assay
EC50
75±n/a nM
Citation
 Griffioen, G; Van Dooren, T; Rojas De La Parra, V; Allasia, S; Marchand, A; Kilonda, A; Chaltin, P Compounds for the treatment of neurodegenerative diseases US Patent  US9266832 Publication Date 2/23/2016 
Target
Name:
Alpha-synuclein
Synonyms:
NACP | PARK1 | SNCA | SYUA_HUMAN
Type:
Protein
Mol. Mass.:
14451.42
Organism:
Homo sapiens (Human)
Description:
P37840
Residue:
140
Sequence:
MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTKEQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDPDNEAYEMPSEEGYQDYEPEA
  
Inhibitor
Name:
BDBM207958
Synonyms:
US9266832, Cpd115
Type:
Small organic molecule
Emp. Form.:
C25H20FN3O
Mol. Mass.:
397.4442
SMILES:
Fc1cccc(Cc2ccc(cc2)C(=O)NCCc2c[nH]c3ccc(cc23)C#N)c1
Structure:
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