Reaction Details
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Olfactory receptor class A-like protein 1
Ligand
BDBM231632
Substrate
n/a
Meas. Tech.
Functional Calcium Imaging Assay
pH
7.4±n/a
EC50
1.48e+4± 1.8e+3 nM
Comments
extracted
Citation
Behrens, M; Frank, O; Rawel, H; Ahuja, G; Potting, C; Hofmann, T; Meyerhof, W; Korsching, S ORA1, a zebrafish olfactory receptor ancestral to all mammalian V1R genes, recognizes 4-hydroxyphenylacetic acid, a putative reproductive pheromone. J Biol Chem 289:19778-88 (2014) [PubMed] Article More Info.:
Target
Name:
Olfactory receptor class A-like protein 1
Synonyms:
ORA1_DANRE | Olfactory receptor class A 1 (ORA1) | Vlr2 | ora1
Type:
Protein
Mol. Mass.:
34536.30
Organism:
Danio rerio (Zebrafish)
Description:
Q597G5
Residue:
316
Sequence:
MDLCVTIKGVSFLLQAGLGILANALVLLAYAHIRLAEARLQPVDAILCHLALVDLLLLLTRGVPQTMTVFGMRNLLDDTGCKVVIYTYRIARALSVCITCMLSVFQAVTVAPAAGPLLSGVKARLPQLLAPTFAALWFINMAVCIAAPFFSVAPRNGTVPPFTLNLGFCHVDFHDNLSYVLNGVAVSVRDFAFVGAMLASSGFILLLLHRHRRQVRAVRRSQGSTMETRAARTVLMLVILYSVFFGIDNVIWIYMLTVAQVPPVVADMRVFFSSCYASLSPFLIISSNRKLKARMVCATSEQERQAEDGKNSSGKN
Inhibitor
Name:
BDBM231632
Synonyms:
4-Toloylacetic acid
Type:
Small organic molecule
Emp. Form.:
C10H10O3
Mol. Mass.:
178.1846
SMILES:
Cc1ccc(cc1)C(=O)CC(O)=O
Structure:
