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Target
5-hydroxytryptamine receptor 7
Ligand
BDBM233046
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
Ki
>1.0e+4±n/a nM
Citation
 Badarau, E; Putey, A; Suzenet, F; Joseph, B; Bojarski, A; Finaru, A; Guillaumet, G New insights into homopiperazine-based 5-HT1A/5-HT7R ligands: synthesis and biological evaluation. J Enzyme Inhib Med Chem 25:301-5 (2010) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 7
Synonyms:
5-HT-7 | 5-HT-X | 5-HT7 | 5-HT7L | 5-HT7S | 5-HT7b | 5HT7 | 5HT7R_HUMAN | HTR7 | Serotonin receptor 7
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
53573.08
Organism:
Homo sapiens (Human)
Description:
P34969
Residue:
479
Sequence:
MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTWDAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALKLAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD
  
Inhibitor
Name:
BDBM233046
Synonyms:
2-[(2-Pyrrolo[2,3-c]pyridin-1-yl)ethyl]decahydropyrido[1,2-a][1,4]diazepine (7)
Type:
Small organic molecule
Emp. Form.:
C18H26N4
Mol. Mass.:
298.4258
SMILES:
C(Cn1ccc2ccncc12)N1CCCN2CCCCC2C1
Structure:
Search PDB for entries with ligand similarity: