Reaction Details Report a problem with these data
Target
L-lactate dehydrogenase A chain
Ligand
BDBM234444
Substrate
n/a
Meas. Tech.
LDH Activity Assay
pH
7.4±n/a
IC50
1750000±n/a nM
Comments
extracted
Citation
 Rodríguez-Páez, L; Chena-Taboada, MA; Cabrera-Hernández, A; Cordero-Martínez, J; Wong, C Oxamic acid analogues as LDH-C4-specific competitive inhibitors. J Enzyme Inhib Med Chem 26:579-86 (2011) [PubMed]  Article 
Target
Name:
L-lactate dehydrogenase A chain
Synonyms:
L-lactate:NAD+ oxidoreductase A (LDH-A4) | LDHA_MOUSE | Ldh-1 | Ldh1 | Ldha
Type:
Enzyme
Mol. Mass.:
36502.66
Organism:
Mus musculus (Mouse)
Description:
P06151
Residue:
332
Sequence:
MATLKDQLIVNLLKEEQAPQNKITVVGVGAVGMACAISILMKDLADELALVDVMEDKLKGEMMDLQHGSLFLKTPKIVSSKDYCVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNIVKYSPHCKLLIVSNPVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHALSCHGWVLGEHGDSSVPVWSGVNVAGVSLKSLNPELGTDADKEQWKEVHKQVVDSAYEVIKLKGYTSWAIGLSVADLAESIMKNLRRVHPISTMIKGLYGINEDVFLSVPCILGQNGISDVVKVTLTPEEEARLKKSADTLWGIQKELQF
  
Inhibitor
Name:
BDBM234444
Synonyms:
N-Propyl oxamate
Type:
Small organic molecule
Emp. Form.:
C5H8NO3
Mol. Mass.:
130.1225
SMILES:
CCCNC(=O)C([O-])=O
Structure:
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