Reaction Details Report a problem with these data
Target
Tyrosine-protein phosphatase non-receptor type 1 [1-321]
Ligand
BDBM50391109
Substrate
n/a
Meas. Tech.
PTP1B Activity Assay
pH
7.5±0
Temperature
310.15±0 K
IC50
25.39±0.65 nM
Citation
 Adisakwattana, S; Pongsuwan, J; Wungcharoen, C; Yibchok-anun, S In vitro effects of cinnamic acid derivatives on protein tyrosine phosphatase 1B. J Enzyme Inhib Med Chem 28:1067-72 (2013) [PubMed]  Article 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 1 [1-321]
Synonyms:
PTN1_HUMAN | PTP1B | PTPN1 | Protein tyrosine phosphatase 1B (PTP1B)
Type:
Enzyme
Mol. Mass.:
37311.71
Organism:
Homo sapiens (Human)
Description:
P18031 (1-321 aa)
Residue:
321
Sequence:
MEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHEDLEPPPEHIPPPPRPPKRILEPHN
  
Inhibitor
Name:
BDBM50391109
Synonyms:
CHEMBL179166 | Sodium orthovanadate (SOV) | Vanadates
Type:
Small organic molecule
Emp. Form.:
O4V
Mol. Mass.:
114.9407
SMILES:
[O-][V]([O-])([O-])=O
Structure:
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