Reaction Details Report a problem with these data
Target
Carbonic anhydrase [110-330]
Ligand
BDBM50159796
Substrate
n/a
Meas. Tech.
Stopped Flow CO2 Hydration Assay
pH
8.3±n/a
Temperature
293.15±n/a K
Ki
51200±n/a nM
Citation
 Dathan, NA; Alterio, V; Troiano, E; Vullo, D; Ludwig, M; De Simone, G; Supuran, CT; Monti, SM Biochemical characterization of the chloroplastic ß-carbonic anhydrase from Flaveria bidentis (L.) "Kuntze". J Enzyme Inhib Med Chem 29:500-4 (2014) [PubMed]  Article 
Target
Name:
Carbonic anhydrase [110-330]
Synonyms:
CAHX_FLABI | Carbonic anhydrase (CA1)
Type:
Enzyme
Mol. Mass.:
24226.97
Organism:
Flaveria bidentis (Coastal plain yellowtops)
Description:
Truncated version without chloroplast transit peptide (1-109)
Residue:
221
Sequence:
QAAAPDTKAPFDPVERIKSGFVKFKTEKFVTNPALYDELAKGQSPKFMVFACSDSRVCPSHVLDFQPGEAFVVRNVANMVPPFDKTKYSGVGAAVEYAVLHLKVQEIFVIGHSRCGGIKGLMTFPDEGPHSTDFIEDWVKVCLPAKSKVVAEHNGTHLDDQCVLCEKEAVNVSLGNLLTYPFVRDGLRNKTLALKGGHYDFVNGTFELWALDFGLSSPTSV
  
Inhibitor
Name:
BDBM50159796
Synonyms:
2,3,5,6-F4-Benzoate | CHEMBL368444 | Sodium; 2,3,5,6-tetrafluoro-benzoate | sodium 2,3,5,6-tetrafluorobenzoate
Type:
Small organic molecule
Emp. Form.:
C7HF4O2
Mol. Mass.:
193.0758
SMILES:
[O-]C(=O)c1c(F)c(F)cc(F)c1F
Structure:
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