Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 1
Ligand
BDBM250218
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
pH
7.4±n/a
Temperature
310.15±n/a K
Ki
0.3±n/a nM
Comments
extracted
Citation
 Groebke Zbinden, K; Norcross, R; Pflieger, P Substituted benzamides US Patent  US9452980 Publication Date 9/27/2016 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TAAR1_RAT | Ta1 | Taar1 | Tar1 | Trace amine receptor 1 (TARR1) | Trace amine-associated receptor 1 | Trace amine-associated receptor 1 (TAAR1) | Trace amine-associated receptor1 | Trar1
Type:
Enzyme
Mol. Mass.:
38034.73
Organism:
Rattus norvegicus (Rat)
Description:
Q923Y9
Residue:
332
Sequence:
MHLCHNSANISHTNSNWSRDVRASLYSLISLIILTTLVGNLIVIISISHFKQLHTPTNWLLHSMAVVDFLLGCLVMPYSMVRTVEHCWYFGELFCKLHTSTDIMLSSASILHLAFISIDRYYAVCDPLRYKAKINLAAIFVMILISWSLPAVFAFGMIFLELNLEGVEELYHNQVFCLRGCFPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRANLQVGLEGESRAPQSKETKAAKTLGIMVGVFLLCWCPFFFCMVLDPFLGYVIPPTLNDTLNWFGYLNSAFNPMVYAFFYPWFRRALKMVLFGKIFQKDSSRSKLFL
  
Inhibitor
Name:
BDBM250218
Synonyms:
US10501411, Example 128 | US11697636, Example 128 | US9452980, 128
Type:
Small organic molecule
Emp. Form.:
C20H23ClN2O2
Mol. Mass.:
358.862
SMILES:
Clc1ccc(CCCOC(=O)Nc2ccc(cc2)C2CCNC2)cc1
Structure:
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