Reaction Details Report a problem with these data
Target
Lysophosphatidic acid receptor 5
Ligand
BDBM251706
Substrate
n/a
Meas. Tech.
Receptor Assay
Temperature
310.15±n/a K
IC50
17±n/a nM
Comments
extracted
Citation
 Buffham, W; Canning, H; Davenport, R; Farnaby, W; Mack, S; Parmar, A; Wright, S Compounds US Patent  US9464060 Publication Date 10/11/2016 
Target
Name:
Lysophosphatidic acid receptor 5
Synonyms:
GPR92 | GPR93 | LPAR5 | LPAR5_HUMAN | Lysophosphatidic acid receptor 5 | Lysophosphatidic acid receptor 5 (LPA5)
Type:
Enzyme
Mol. Mass.:
41372.36
Organism:
Homo sapiens (Human)
Description:
Q9H1C0
Residue:
372
Sequence:
MLANSSSTNSSVLPCPDYRPTHRLHLVVYSLVLAAGLPLNALALWVFLRALRVHSVVSVYMCNLAASDLLFTLSLPVRLSYYALHHWPFPDLLCQTTGAIFQMNMYGSCIFLMLINVDRYAAIVHPLRLRHLRRPRVARLLCLGVWALILVFAVPAARVHRPSRCRYRDLEVRLCFESFSDELWKGRLLPLVLLAEALGFLLPLAAVVYSSGRVFWTLARPDATQSQRRRKTVRLLLANLVIFLLCFVPYNSTLAVYGLLRSKLVAASVPARDRVRGVLMVMVLLAGANCVLDPLVYYFSAEGFRNTLRGLGTPHRARTSATNGTRAALAQSERSAVTTDATRPDAASQGLLRPSDSHSLSSFTQCPQDSAL
  
Inhibitor
Name:
BDBM251706
Synonyms:
US10100018, Example 42 | US9464060, 42
Type:
Small organic molecule
Emp. Form.:
C25H21ClFNO4
Mol. Mass.:
453.89
SMILES:
OC(=O)c1ccc(CN(CC2CC2)C(=O)c2ccc(Oc3c(F)cccc3Cl)cc2)cc1
Structure:
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