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TargetMelanin-concentrating hormone receptor 1 (MCHR1)(E4Q)(A5T)
LigandBDBM258619
Substrate/Competitorn/a
Meas. Tech.Radioligand Binding Assay
pH7.4±n/a
Ki 3±n/a nM
Commentsextracted
Citation Washburn, WNMurugaiah Subbaiah, MAAhmad, S Pyrrolone or pyrrolidinone melanin concentrating hormone receptor-1 antagonists US Patent US9499482 Publication Date 11/22/2016
More Info.:Get all data from this article,  Assay Method
 
Melanin-concentrating hormone receptor 1 (MCHR1)(E4Q)(A5T)
Name:Melanin-concentrating hormone receptor 1 (MCHR1)(E4Q)(A5T)
Synonyms:n/a
Type:Enzyme
Mol. Mass.:46077.38
Organism:Homo sapiens (Human)
Description:Q99705 (E4Q, A5T)
Residue:422
Sequence:
MSVQTMKKGVGRAVGLGGGSGCQATEEDPLPNCGACAPGQGGRRWRLPQPAWVEGSSARL
WEQATGTGWMDLEASLLPTGPNASNTSDGPDNLTSAGSPPRTGSISYINIIMPSVFGTIC
LLGIIGNSTVIFAVVKKSKLHWCNNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHF
GETMCTLITAMDANSQFTSTYILTAMAIDRYLATVHPISSTKFRKPSVATLVICLLWALS
FISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVRI
LQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVY
LYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRAVSNAQTADEERTESK
GT
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  Blast E-value cutoff:
BDBM258619
NameBDBM258619
Synonyms:US9499482, 18
TypeSmall organic molecule
Emp. Form.C28H37N3O4
Mol. Mass.479.6111
SMILESCOc1cc(ccc1OCCN1CC[C@H](C1)N(C)C)N1CC[C@H](Oc2ccc(cc2)C2CC2)C1=O |r|
Structure
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n/a