Assay Method Information

Assay Name:  Counterscreen for inhibitors of COUP-TFII (NR2F2): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16)
Description:  Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provider: Ming-Jer Tsai, Baylor College of Medicine Network: Molecular Library Probe Production Centers Network (MLPCN) Grant Proposal Number: R01DK45641 Grant Proposal PI: Ming-Jer Tsai, Baylor College of Medicine External Assay ID: VP16_INH_LUMI_1536_3XIC50 DCSRUN for COUP-TFII (NR2F2) Name: Counterscreen for inhibitors of COUP-TFII (NR2F2): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16). Description: Steroid receptor chicken ovalbumin upstream promoter-transcription factor II (COUP-TFII) (1), an orphan nuclear receptor and member of the nuclear receptor superfamily, has been shown to be a critical transcriptional regulator in many different cancer types by promoting angiogenesis (2-4), cell proliferation and metastasis (5-11). COUP-TFII has widespread ti
Affinity data for this assay
 

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