| Assay Method Information | |
| | TRbeta-Binding Assay and Thyroid Response Element (TRAFbeta1) Reporter Assay. |
| Description: | IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. EC50 is the concentration of compound required to reach or inhibit (agonist or antagonist) 50% of T3-induced TRbeta-activation in CHOK1 cells stably transfected with hTRbeta using alkaline phosphatase reporter assay. |
| Affinity data for this assay | |
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