Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 1AOE
TargetDihydrofolate reductase(Yeast)
Gsk

LigandPNGBDBM18043(CHEMBL318721 | 5-(pentan-3-yl)-5,10,12-triazatricy...)
Affinity DataIC50: 4nMpH: 6.4 T: 2°CAssay Description:IC50 is the concentration of inhibitor that decreases the velocity of the standard assay by 50%. The enzyme, NADPH, and varying concentrations of inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydrofolate reductase(Yeast)
Gsk

LigandPNGBDBM18043(CHEMBL318721 | 5-(pentan-3-yl)-5,10,12-triazatricy...)
Affinity DataKi:  0.220nMAssay Description:Inhibition of Dihydrofolate reductase enzyme from Candida albicansMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)