Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 1DMK
TargetNitric oxide synthase, endothelial(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50055281(2-Ethyl-isothiourea | S-ethyl-iso-thiourea | S-ETH...)
Affinity DataIC50: 1.30E+3nMAssay Description:The compound was evaluated for the inhibitory potencies using human Endothelial nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, endothelial(Pig)
Julius-Maximilians University WüRzburg

Curated by ChEMBL
LigandPNGBDBM50081594(6-phenyl-5,6,7,8-tetrahydropteridine-2,4-diamine |...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibitory activity against Nitric oxide synthase (derived from porcine brain cerebellum)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, endothelial(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50055281(2-Ethyl-isothiourea | S-ethyl-iso-thiourea | S-ETH...)
Affinity DataKi:  39nMAssay Description:Inhibition of eNOS in human DLD-1 cells assessed as reduction of L-[14C]arginine to L-[14C]citrulline conversionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)