Compile Data Set for Download or QSAR
Report error Found 1 Enz. Inhib. hit(s) for PDB: 1IA3
TargetDihydrofolate reductase(Yeast)
Gsk

LigandPNGBDBM18047(5-[(4-tert-butylphenyl)sulfanyl]quinazoline-2,4-di...)
Affinity DataIC50: 8nMpH: 6.4 T: 2°CAssay Description:IC50 is the concentration of inhibitor that decreases the velocity of the standard assay by 50%. The enzyme, NADPH, and varying concentrations of inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)