Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 1NL9
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM13953(2-({4-[2-acetamido-2-(pentylcarbamoyl)ethyl]naphth...)
Affinity DataKi:  631nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM13953(2-({4-[2-acetamido-2-(pentylcarbamoyl)ethyl]naphth...)
Affinity DataKi:  1.10E+3nM ΔG°:  -33.7kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM13953(2-({4-[2-acetamido-2-(pentylcarbamoyl)ethyl]naphth...)
Affinity DataKi:  1.10E+3nMAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM13953(2-({4-[2-acetamido-2-(pentylcarbamoyl)ethyl]naphth...)
Affinity DataKi:  1.10E+3nMAssay Description:Binding affinity for Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)