Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 1O5M
LigandPNGBDBM14433(4-[2-(4-{6,15-dibromo-13-chloro-4-azatricyclo[9.4....)
Affinity DataIC50: 8.30nMpH: 7.5 T: 2°CAssay Description:The in vitro activity of compounds inhibiting FTase was determined by measuring the transfer of [3H]-FPP to substrate Ha-Ras-CVLS. The incorporated r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM14433(4-[2-(4-{6,15-dibromo-13-chloro-4-azatricyclo[9.4....)
Affinity DataIC50: 8.30nMpH: 7.5 T: 2°CAssay Description:The in vitro activity of compounds inhibiting FTase was determined by measuring the transfer of [3H]-FPP to substrate Ha-Ras-CVLS. The incorporated r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM14433(4-[2-(4-{6,15-dibromo-13-chloro-4-azatricyclo[9.4....)
Affinity DataIC50: 1.00E+4nMAssay Description:The in vitro activity of compounds inhibiting FTase was determined by measuring the transfer of [3H]-FPP to substrate Ha-Ras-CVLS. The incorporated r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM14433(4-[2-(4-{6,15-dibromo-13-chloro-4-azatricyclo[9.4....)
Affinity DataIC50: 1.00E+4nMAssay Description:The in vitro activity of compounds inhibiting FTase was determined by measuring the transfer of [3H]-FPP to substrate Ha-Ras-CVLS. The incorporated r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)