Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) for PDB: 1W0X
LigandPNGBDBM5718(2,6,9-Trisubstituted purine deriv. 26 | 2-{[6-(ben...)
Affinity DataIC50: 1.20E+3nMpH: 7.4 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM5718(2,6,9-Trisubstituted purine deriv. 26 | 2-{[6-(ben...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CDK2/cyclin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM5718(2,6,9-Trisubstituted purine deriv. 26 | 2-{[6-(ben...)
Affinity DataIC50: 7.00E+3nMAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2005
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Human)
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM5718(2,6,9-Trisubstituted purine deriv. 26 | 2-{[6-(ben...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of Cyclin A-cyclin-dependent kinase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM5718(2,6,9-Trisubstituted purine deriv. 26 | 2-{[6-(ben...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of Cyclin E-cyclin-dependent kinase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 2(Human)
Csir-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM5718(2,6,9-Trisubstituted purine deriv. 26 | 2-{[6-(ben...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Human)
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM5718(2,6,9-Trisubstituted purine deriv. 26 | 2-{[6-(ben...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human recombinant CDK2/cyclin A expressed in baculovirus-infected insect Sf21 cells after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM5718(2,6,9-Trisubstituted purine deriv. 26 | 2-{[6-(ben...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CDK2/cyclin A expressed in baculovirus infected insect Sf21 cells using [gamma-P32]ATP and histone H1 as substrate after 10 mins by rad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM5718(2,6,9-Trisubstituted purine deriv. 26 | 2-{[6-(ben...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article
PDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 2(Human)
Csir-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM5718(2,6,9-Trisubstituted purine deriv. 26 | 2-{[6-(ben...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of Cyclin-dependent kinase 2 (CDK2/cyclin A)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 2(Human)
Csir-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM5718(2,6,9-Trisubstituted purine deriv. 26 | 2-{[6-(ben...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CDK2/Cyclin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 2(Human)
Csir-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM5718(2,6,9-Trisubstituted purine deriv. 26 | 2-{[6-(ben...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CDK2/Cyclin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 2(Human)
Csir-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM5718(2,6,9-Trisubstituted purine deriv. 26 | 2-{[6-(ben...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM5718(2,6,9-Trisubstituted purine deriv. 26 | 2-{[6-(ben...)
Affinity DataIC50: 7.08E+3nMAssay Description:Inhibition of CDK2/Cyclin E (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Human)
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM5718(2,6,9-Trisubstituted purine deriv. 26 | 2-{[6-(ben...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant CDK2/cyclin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM5718(2,6,9-Trisubstituted purine deriv. 26 | 2-{[6-(ben...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant CDK2/cyclin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)