Affinity DataIC50: 3nMAssay Description:Inhibition of domain-GST fused human wild-type EGFR expressing in Sf9 cells using pEY (4:1) and bio-pEY as substrate for 30 min in the presence of AT...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 8nMAssay Description:Inhibition of domain-GST fused human EGFR L858R mutant expressing in Sf9 cells using pEY (4:1) and bio-pEY as substrate for 30 min in the presence of...More data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:Inhibition of EGFR L858R mutant expressing in human NCI-H3255 cells assessed as cell survival incubated for 2 weeks and measured after 6 hrs by MTS a...More data for this Ligand-Target Pair
Affinity DataEC50: 105nMAssay Description:Inhibition of EGFR-phosphorylation in EGFR expressing human A-431 cells incubated for 1 hr followed by EGF stimulation for 20 min by ELISA methodMore data for this Ligand-Target Pair
Affinity DataIC50: 534nMAssay Description:Inhibition of wild-type EGFR expressing in human NCI-H1666 cells assessed as cell survival incubated for 2 weeks and measured after 6 hrs by MTS assa...More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of EGFR L858R/T790M double mutant expressing in human NCI-H1975 cells assessed as cell survival incubated for 2 weeks and measured after 6...More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of domain-GST fused human EGFR L858R/T790M double mutant expressing in Sf9 cells using pEY (4:1) and bio-pEY as substrate for 30 min in th...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin) using poly(Glu-Tyr) at 4:1 ratio as substrate in presence of ATP incubated for 60 mins ...More data for this Ligand-Target Pair
