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Report error Found 4 Enz. Inhib. hit(s) for PDB: 1XLX

cAMP-specific 3',5'-cyclic phosphodiesterase 4D [372-376,381-715,S375G,I381V,S383G,G384S,V385H,K386M)(Human)
Plexxikon

BDBM14773(Ariflo | 4-cyano-4-[3-(cyclopentyloxy)-4-methoxyph...)

IC50: 11nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
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Date in BDB:
4/9/2007
Entry Details Article
PubMed PDB

3D Structure (crystal)

cAMP-specific 3',5'-cyclic phosphodiesterase 4B [316-320,321-700,S319G,N320S,N321H,T322M](Human)
Plexxikon

BDBM14773(Ariflo | 4-cyano-4-[3-(cyclopentyloxy)-4-methoxyph...)

IC50: 25nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

Purchase ChEBI
PC cid PC sid PDB Similars

Date in BDB:
4/9/2007
Entry Details Article
PubMed PDB

3D Structure (crystal)

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Rat)
University of Tennessee

Curated by PDSP K_i Database