Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 2B36
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM16296(5-pentyl-2-phenoxylphenol | 5-Pentyl-2-phenoxy-phe...)
Affinity DataKi:  11.8nM ΔG°:  -44.8kJ/molepH: 6.8 T: 2°CAssay Description:Inhibition constants (Ki) were calculated by determining the kcat and Km (DDCoA) values at several fixed inhibitor concentrations. The inhibition dat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM16296(5-pentyl-2-phenoxylphenol | 5-Pentyl-2-phenoxy-phe...)
Affinity DataIC50: 17nMpH: 6.8 T: 2°CAssay Description:The assay measured the NADH-dependent catalysis of a DD-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to NAD. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)