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Found
2
Enz. Inhib. hit(s) for PDB:
2E9P
Target
Serine/threonine-protein kinase Chk1
(Human)
Abbott Laboratories
Ligand
BDBM15246
(3-(5-chloro-2-methoxyphenyl)-1-(6-{[1-(dimethylami...)
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Affinity Data
IC50: 22nM
pH: 7.4 T: 2°C
Assay Description:
Chk1 kinase activity was assayed in reaction buffer containing substrate, enzyme, and inhibitor in the presence of 5uM ATP/[gamma-33P] ATP. 33P incor...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
5/7/2007
Entry Details
Article
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PubMed
PDB
3D Structure (crystal)
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Target
Serine/threonine-protein kinase Chk1
(Human)
Abbott Laboratories
Ligand
BDBM15246
(3-(5-chloro-2-methoxyphenyl)-1-(6-{[1-(dimethylami...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 20nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
5/21/2013
Entry Details
Article
Copy Entry DOI
PubMed
PDB
3D Structure (crystal)
Copy Rxn URL