Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 2ETK
TargetRho-associated protein kinase 1(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50027431(Hydroxy-Fasudil | HYDROXYFASUDIL)
Affinity DataIC50: 720nMAssay Description:Inhibition of ROCK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetRho-associated protein kinase 1(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50027431(Hydroxy-Fasudil | HYDROXYFASUDIL)
Affinity DataIC50: 800nMAssay Description:Inhibition of ROCK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetRho-associated protein kinase 1(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50027431(Hydroxy-Fasudil | HYDROXYFASUDIL)
Affinity DataKi:  150nMAssay Description:Inhibition of human ROCK1 by homogenous luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRho-associated protein kinase 1(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50027431(Hydroxy-Fasudil | HYDROXYFASUDIL)
Affinity DataKi:  150nMAssay Description:Inhibition of human leukocytic ROCK1 expressed in insect cells using KKRNRTLSV as substrate after 10 mins by pyruvate kinase/lactate dehydrogenase co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)