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Found
1
Enz. Inhib. hit(s) for PDB:
2H96
Target
Mitogen-activated protein kinase 8
(Human)
Abbott Laboratories
Ligand
BDBM15922
(5-cyano-N-[(2,5-dimethoxyphenyl)methyl]-6-ethoxypy...)
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Affinity Data
IC50: 230nM
pH: 7.2 T: 2°C
Assay Description:
In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...
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Target Info
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Ligand Info
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In Depth
Date in BDB:
5/24/2007
Entry Details
Article
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PubMed
PDB
3D Structure (crystal)
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