Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 2IPW
TargetAldo-keto reductase family 1 member B1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM16429(CHEMBL240293 | EINECS 229-504-0 | 2-(2,6-dichlorop...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B1 [W220Y,C299A](Human)
Medical College of Wiscosin

LigandPNGBDBM16429(CHEMBL240293 | EINECS 229-504-0 | 2-(2,6-dichlorop...)
Affinity DataKi:  1.00E+3nMAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM16429(CHEMBL240293 | EINECS 229-504-0 | 2-(2,6-dichlorop...)
Affinity DataKi:  4.40E+3nM ΔG°:  -30.6kJ/molepH: 7.0 T: 2°CAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)