Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 2ISF
TargetAldo-keto reductase family 1 member B1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM16419(Phenylacetate, XIX | Benzeneacetic acid | phenylac...)
Affinity DataIC50: 9.60E+4nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM16419(Phenylacetate, XIX | Benzeneacetic acid | phenylac...)
Affinity DataKi:  9.60E+4nM ΔG°:  -22.9kJ/molepH: 7.0 T: 2°CAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B1 [C299A](Human)
Medical College of Wiscosin

LigandPNGBDBM16419(Phenylacetate, XIX | Benzeneacetic acid | phenylac...)
Affinity DataKi:  3.03E+5nMAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B1 [W220Y,C299A](Human)
Medical College of Wiscosin

LigandPNGBDBM16419(Phenylacetate, XIX | Benzeneacetic acid | phenylac...)
Affinity DataKi:  3.60E+5nMAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)