Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 2OFU
TargetTyrosine-protein kinase Lck(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50080265(2-Amino-3-(4-phosphonooxy-phenyl)-propionic acid |...)
Affinity DataKd:  4.00E+5nMAssay Description:Binding affinity against Lck SH2 domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase Lck(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM17744(2,6-dimethylphenyl N-[2-({3,5-dimethoxy-4-[3-(4-me...)
Affinity DataIC50: 0.600nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)