Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 2OS2
TargetLysine-specific demethylase 4A(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM26106(CHEMBL90852 | Oxalylglycine | [(carboxymethyl)carb...)
Affinity DataIC50: 8.50E+4nMAssay Description:Inhibition of C-terminal FLAG-tagged human KDM4A expressed in Escherichia coli pre-incubated for 4 hrs before substrate addition and measured after 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLysine-specific demethylase 4A(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM26106(CHEMBL90852 | Oxalylglycine | [(carboxymethyl)carb...)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of recombinant His-tagged JMJD2A expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells by formaldehyde dehydrogenase-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLysine-specific demethylase 4A(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM26106(CHEMBL90852 | Oxalylglycine | [(carboxymethyl)carb...)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of KDM4AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLysine-specific demethylase 4A(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM26106(CHEMBL90852 | Oxalylglycine | [(carboxymethyl)carb...)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of KDM4A (unknown origin) using H3K9me3 peptide and 2-oxoglutarate as substrate after 1 hr by FDH-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)