Report error Found 5 Enz. Inhib. hit(s) for PDB: 2RFN
TargetHepatocyte growth factor receptor(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)
Curated by ChEMBL
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)
Curated by ChEMBL
Affinity DataIC50: 8.90nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
3D Structure (crystal)TargetHepatocyte growth factor receptor(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)
Curated by ChEMBL
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)
Curated by ChEMBL
Affinity DataKi: 8.90nM ΔG°: -45.5kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)
Curated by ChEMBL
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)
Curated by ChEMBL
Affinity DataIC50: 8.90nMAssay Description:Inhibition of wild type GST-tagged c-Met kinase domain (1058 to 1365) (unknown origin) expressed in Sf9 cells by HTRF assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)
Curated by ChEMBL
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)
Curated by ChEMBL
Affinity DataIC50: 8.90nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)
Curated by ChEMBL
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair