Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 2V3E
TargetLysosomal acid glucosylceramidase(Human)
Nankai University

LigandPNGBDBM50156357(CHEMBL187158 | NN-DNJ | 2-Hydroxymethyl-1-nonyl-pi...)
Affinity DataIC50: 668nMpH: 7.0Assay Description:The assays were performed at 37°C with 4-MU-β-ᴅ-Glu as the substrate in Mcllvaine buffer (sodium citrate (100mM) and sodium phosphate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLysosomal acid glucosylceramidase(Human)
Nankai University

LigandPNGBDBM50156357(CHEMBL187158 | NN-DNJ | 2-Hydroxymethyl-1-nonyl-pi...)
Affinity DataIC50: 979nMpH: 5.2Assay Description:The assays were performed at 37°C with 4-MU-β-ᴅ-Glu as the substrate in Mcllvaine buffer (sodium citrate (100mM) and sodium phosphate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLysosomal acid glucosylceramidase(Human)
Nankai University

LigandPNGBDBM50156357(CHEMBL187158 | NN-DNJ | 2-Hydroxymethyl-1-nonyl-pi...)
Affinity DataKi:  488nMpH: 5.2Assay Description:To determine inhibition constant (Ki), substrate (7.5µL, various concentrations in Mcllvaine buffer, pH 5.2) and enzyme (12.5µL, 0.1mg/mL) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)