Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 2V60
TargetAmine oxidase [flavin-containing] B(Rat)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM19189(C17 | 7-[(3-chlorophenyl)methoxy]-2-oxo-2H-chromen...)
Affinity DataIC50: 52nMAssay Description:Inhibition of Sprague-Dawley rat MAO-B using Kynuramine as substrate assessed as formation of 4-hydroxyquinoline preincubated for 5 mins prior to sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAmine oxidase [flavin-containing] B(Rat)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM19189(C17 | 7-[(3-chlorophenyl)methoxy]-2-oxo-2H-chromen...)
Affinity DataIC50: 52nMAssay Description:Inhibition of Sprague-Dawley rat MAO-B in brain mitochondrial homogenate assessed as 4-hydroxyquinoline by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAmine oxidase [flavin-containing] B(Human)
University of Pavia

LigandPNGBDBM19189(C17 | 7-[(3-chlorophenyl)methoxy]-2-oxo-2H-chromen...)
Affinity DataKi:  400nM ΔG°:  -36.5kJ/molepH: 7.5 T: 2°CAssay Description:MAO B activities were determined spectrophotometrically at 250 nm using benzylamine as substrate. Competitive Ki values were determined by measuring ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)