Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) for PDB: 2W3B
TargetDihydrofolate reductase(Human)
Lindsley F. Kimball Research Institute

Curated by ChEMBL
LigandPNGBDBM50034929(6-{[(2,5-DIETHOXYPHENYL)AMINO]METHYL}-5-METHYLPYRI...)
Affinity DataIC50: 0.840nMAssay Description:Antimycobacterial activity against Mycobacterium avium complex dihydrofolate reductase (MAC DHFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50034929(6-{[(2,5-DIETHOXYPHENYL)AMINO]METHYL}-5-METHYLPYRI...)
Affinity DataIC50: 17.4nMAssay Description:Inhibitory activity against Dihydrofolate reductase from rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50034929(6-{[(2,5-DIETHOXYPHENYL)AMINO]METHYL}-5-METHYLPYRI...)
Affinity DataIC50: 17.4nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50034929(6-{[(2,5-DIETHOXYPHENYL)AMINO]METHYL}-5-METHYLPYRI...)
Affinity DataIC50: 370nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydrofolate reductase(Human)
Lindsley F. Kimball Research Institute

Curated by ChEMBL
LigandPNGBDBM50034929(6-{[(2,5-DIETHOXYPHENYL)AMINO]METHYL}-5-METHYLPYRI...)
Affinity DataIC50: 2.30E+3nMAssay Description:Antimycobacterial activity against human dihydrofolate reductase (hDHFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)