Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) for PDB: 2WHO
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35553(1H-benzo[de]isoquinoline-1,3(2H)-dione, 1)
Affinity DataIC50: 20nM EC50:  7.10E+3nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM35553(1H-benzo[de]isoquinoline-1,3(2H)-dione, 1)
Affinity DataIC50: 20nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35553(1H-benzo[de]isoquinoline-1,3(2H)-dione, 1)
Affinity DataIC50: 64nMAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM35553(1H-benzo[de]isoquinoline-1,3(2H)-dione, 1)
Affinity DataIC50: 78nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM35553(1H-benzo[de]isoquinoline-1,3(2H)-dione, 1)
Affinity DataIC50: 500nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM35553(1H-benzo[de]isoquinoline-1,3(2H)-dione, 1)
Affinity DataIC50: 1.00E+3nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)