Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 2WX2
TargetSterol 14-alpha demethylase(Trypanosoma cruzi (strain CL Brener))
Vanderbilt University

LigandPNGBDBM25817(Fungata | Diflucan | Fluconazole (f) | cid_3365 | ...)
Affinity DataKd:  230nMpH: 6.0Assay Description:Azole derivatives used as an inhibitor of TB and TC CYP51.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLanosterol 14-alpha-demethylase(Trypanosoma brucei brucei (strain 927/4 GUTat10.1))
Vanderbilt University

LigandPNGBDBM25817(Fungata | Diflucan | Fluconazole (f) | cid_3365 | ...)
Affinity DataKd:  340nMpH: 6.0Assay Description:Azole derivatives used as an inhibitor of TB and TC CYP51.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSterol 14-alpha demethylase(Trypanosoma cruzi (strain CL Brener))
Vanderbilt University

LigandPNGBDBM25817(Fungata | Diflucan | Fluconazole (f) | cid_3365 | ...)
Affinity DataIC50: 880nMAssay Description:Inhibition of recombinant Trypanosoma cruzi Tulahuen CYP51 expressed in Escherichia coli JM109 cell membranes assessed as inhibition of microbe growt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)